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SMRT and NCoR1 fine-tune inflammatory versus tolerogenic balance in dendritic cells by differentially regulating STAT3 signaling

Dendritic cell (DC) fine-tunes inflammatory versus tolerogenic responses to protect from immune-pathology. However, the role of co-regulators in maintaining this balance is unexplored. NCoR1-mediated repression of DC immune-tolerance has been recently reported. Here we found that depletion of NCoR1...

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Detalles Bibliográficos
Autores principales: Jha, Atimukta, Ahad, Abdul, Mishra, Gyan Prakash, Sen, Kaushik, Smita, Shuchi, Minz, Aliva Prity, Biswas, Viplov Kumar, Tripathy, Archana, Senapati, Shantibhushan, Gupta, Bhawna, Acha-Orbea, Hans, Raghav, Sunil Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9552960/
https://www.ncbi.nlm.nih.gov/pubmed/36238311
http://dx.doi.org/10.3389/fimmu.2022.910705