Cyclophilin A/CD147 signaling induces the epithelial-to-mesenchymal transition and renal fibrosis in chronic allograft dysfunction by regulating p38 MAPK signaling

OBJECTIVE: Our study was designed to explore the role of Cyclophilin A (CyPA)/CD147 signaling in renal allograft fibrosis and chronic allograft dysfunction (CAD). MATERIALS AND METHODS: A rat renal transplant model with significant CAD was successfully achieved. Renal allograft tissues and blood sam...

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Detalles Bibliográficos
Autores principales: Liu, Xuzhong, Tang, Zhiwang, Jiang, Xi, Wang, Tianwei, Zhao, Lun, Xu, Zongyuan, Liu, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553177/
https://www.ncbi.nlm.nih.gov/pubmed/36203223
http://dx.doi.org/10.1080/0886022X.2022.2126788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553177/
https://www.ncbi.nlm.nih.gov/pubmed/36203223
http://dx.doi.org/10.1080/0886022X.2022.2126788

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