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Echinatin mitigates sevoflurane-induced hippocampal neurotoxicity and cognitive deficits through mitigation of iron overload and oxidative stress

CONTEXT: Sevoflurane (Sev) is a commonly used surgical anaesthetic; it has neurotoxic effects on the brain. Echinatin (Ech) is reported to have anti-inflammatory and antioxidant activity. OBJECTIVE: This research confirms the effect of Ech on Sev-induced neurotoxicity and cognitive deficits. MATERIA...

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Detalles Bibliográficos
Autores principales: Xu, Zilong, You, Yanqiu, Tang, Qiuqin, Zeng, Hui, Zhao, Tianshou, Wang, Juan, Li, Fujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553189/
https://www.ncbi.nlm.nih.gov/pubmed/36205592
http://dx.doi.org/10.1080/13880209.2022.2123941