Constructing an atlas of associations between polygenic scores from across the human phenome and circulating metabolic biomarkers

BACKGROUND: Polygenic scores (PGS) are becoming an increasingly popular approach to predict complex disease risk, although they also hold the potential to develop insight into the molecular profiles of patients with an elevated genetic predisposition to disease. METHODS: We sought to construct an at...

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Detalles Bibliográficos
Autores principales: Fang, Si, Holmes, Michael V, Gaunt, Tom R, Davey Smith, George, Richardson, Tom G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Epidemiology and Global Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553209/
https://www.ncbi.nlm.nih.gov/pubmed/36219204
http://dx.doi.org/10.7554/eLife.73951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553209/
https://www.ncbi.nlm.nih.gov/pubmed/36219204
http://dx.doi.org/10.7554/eLife.73951

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