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Constructing an atlas of associations between polygenic scores from across the human phenome and circulating metabolic biomarkers
BACKGROUND: Polygenic scores (PGS) are becoming an increasingly popular approach to predict complex disease risk, although they also hold the potential to develop insight into the molecular profiles of patients with an elevated genetic predisposition to disease. METHODS: We sought to construct an at...
Autores principales: | Fang, Si, Holmes, Michael V, Gaunt, Tom R, Davey Smith, George, Richardson, Tom G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553209/ https://www.ncbi.nlm.nih.gov/pubmed/36219204 http://dx.doi.org/10.7554/eLife.73951 |
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