Cannabinoid signaling modulation through JZL184 restores key phenotypes of a mouse model for Williams–Beuren syndrome

Williams–Beuren syndrome (WBS) is a rare genetic multisystemic disorder characterized by mild-to-moderate intellectual disability and hypersocial phenotype, while the most life-threatening features are cardiovascular abnormalities. Nowadays, there are no pharmacological treatments to directly amelio...

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Detalles Bibliográficos
Autores principales: Navarro-Romero, Alba, Galera-López, Lorena, Ortiz-Romero, Paula, Llorente-Ovejero, Alberto, de los Reyes-Ramírez, Lucía, Bengoetxea de Tena, Iker, Garcia-Elias, Anna, Mas-Stachurska, Aleksandra, Reixachs-Solé, Marina, Pastor, Antoni, de la Torre, Rafael, Maldonado, Rafael, Benito, Begoña, Eyras, Eduardo, Rodríguez-Puertas, Rafael, Campuzano, Victoria, Ozaita, Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553213/
https://www.ncbi.nlm.nih.gov/pubmed/36217821
http://dx.doi.org/10.7554/eLife.72560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553213/
https://www.ncbi.nlm.nih.gov/pubmed/36217821
http://dx.doi.org/10.7554/eLife.72560

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