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Cannabinoid signaling modulation through JZL184 restores key phenotypes of a mouse model for Williams–Beuren syndrome
Williams–Beuren syndrome (WBS) is a rare genetic multisystemic disorder characterized by mild-to-moderate intellectual disability and hypersocial phenotype, while the most life-threatening features are cardiovascular abnormalities. Nowadays, there are no pharmacological treatments to directly amelio...
Autores principales: | Navarro-Romero, Alba, Galera-López, Lorena, Ortiz-Romero, Paula, Llorente-Ovejero, Alberto, de los Reyes-Ramírez, Lucía, Bengoetxea de Tena, Iker, Garcia-Elias, Anna, Mas-Stachurska, Aleksandra, Reixachs-Solé, Marina, Pastor, Antoni, de la Torre, Rafael, Maldonado, Rafael, Benito, Begoña, Eyras, Eduardo, Rodríguez-Puertas, Rafael, Campuzano, Victoria, Ozaita, Andres |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553213/ https://www.ncbi.nlm.nih.gov/pubmed/36217821 http://dx.doi.org/10.7554/eLife.72560 |
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