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Cannabinoid receptor-2 attenuates neuroinflammation by promoting autophagy-mediated degradation of the NLRP3 inflammasome post spinal cord injury

BACKGROUND: Neuroinflammation following spinal cord injury (SCI) results in prolonged neurological damage and locomotor dysfunction. Polarization of microglia is vital to regulation of neuroinflammation, although the underlying mechanisms have not yet been elucidated. Endocannabinoid receptor subtyp...

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Detalles Bibliográficos
Autores principales: Jiang, Fan, Xia, Mingjie, Zhang, Yanan, Chang, Jie, Cao, Jiang, Zhang, Zhongkai, Qian, Zhanyang, Yang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553321/
https://www.ncbi.nlm.nih.gov/pubmed/36238284
http://dx.doi.org/10.3389/fimmu.2022.993168