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Oxidative-Damaged Mitochondria Activate GABARAPL1-Induced NLRP3 Inflammasomes in an Autophagic-Exosome Manner after Acute Myocardial Ischemia

OBJECTIVE: This study is aimed at identifying the potential diagnostic markers for circulating endothelial cells (CECs) for acute myocardial ischemia (AMI) and exploring the regulatory mechanisms of the selected biomarker in mitochondrial oxidative damage and vascular inflammation in AMI pathology....

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Detalles Bibliográficos
Autores principales: Zhang, Tiechun, Hou, Dongyao, He, Jianrong, Zeng, Xue, Liu, Ruixue, Liu, Liangming, Li, Tao, Xiao, Yingbin, Ma, Ruiyan, Huang, He, Duan, Chenyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553392/
https://www.ncbi.nlm.nih.gov/pubmed/36238641
http://dx.doi.org/10.1155/2022/7958542