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FAIM Enhances the Efficacy of Mesenchymal Stem Cell Transplantation by Inhibiting JNK-Induced c-FLIP Ubiquitination and Degradation

BACKGROUND: The poor survival rates of transplanted mesenchymal stem cells (MSCs) in harsh microenvironments impair the efficacy of MSCs transplantation in myocardial infarction (MI). Extrinsic apoptosis pathways play an important role in the apoptosis of transplanted MSCs, and Fas apoptosis inhibit...

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Detalles Bibliográficos
Autores principales: Chen, Jinyong, Liu, Feng, Hu, Wangxing, Qian, Yi, Xu, Dilin, Gao, Chenyang, Zeng, Zhiru, Cheng, Si, Xie, Lan, Yu, Kaixiang, Zhu, Gangjie, Liu, Xianbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553537/
https://www.ncbi.nlm.nih.gov/pubmed/36248256
http://dx.doi.org/10.1155/2022/3705637