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Determination of Scopolamine Distribution in Plasma and Brain by LC-MS/MS in Rats

Scopolamine, as a tropane alkaloid found in plants such as belladonna and datura, is used clinically as a transdermal patch and is highly neurotoxic. This study aimed to develop a simple, sensitive, and selective LC-MS/MS method for the determination of the content and distribution of scopolamine in...

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Detalles Bibliográficos
Autores principales: Chen, Juan, Lu, Anjing, Tan, Daopeng, Zhang, Qianru, Lu, Yanliu, Qin, Lin, He, Yuqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553649/
https://www.ncbi.nlm.nih.gov/pubmed/36245782
http://dx.doi.org/10.1155/2022/8536235