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Determination of Scopolamine Distribution in Plasma and Brain by LC-MS/MS in Rats
Scopolamine, as a tropane alkaloid found in plants such as belladonna and datura, is used clinically as a transdermal patch and is highly neurotoxic. This study aimed to develop a simple, sensitive, and selective LC-MS/MS method for the determination of the content and distribution of scopolamine in...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553649/ https://www.ncbi.nlm.nih.gov/pubmed/36245782 http://dx.doi.org/10.1155/2022/8536235 |