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The complex relationship between antibody titers and clinical outcome in botulinum toxin type A long-term treated patients with cervical dystonia

BACKGROUND: Repeated injections with abo- or onabotulinumtoxin type A (aboBoNT/A, onaBoNT/A) may lead to induction of neutralizing antibodies (NABs) and/or a secondary treatment failure (STF). The relation between NABs and STF is still unclear. AIM OF THE STUDY: To demonstrate that a significant imp...

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Detalles Bibliográficos
Autores principales: Hefter, Harald, Ürer, Beyza, Brauns, Raphaela, Rosenthal, Dietmar, Meuth, Sven G., Lee, John-Ih, Albrecht, Philipp, Samadzadeh, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553769/
https://www.ncbi.nlm.nih.gov/pubmed/35842881
http://dx.doi.org/10.1007/s00415-022-11235-3