Genomic architecture of FGFR2 fusions in cholangiocarcinoma and its implication for molecular testing

BACKGROUND: Cholangiocarcinoma (CCA) is a primary malignancy of the biliary tract with a dismal prognosis. Recently, several actionable genetic aberrations were identified with significant enrichment in intrahepatic CCA, including FGFR2 gene fusions with a prevalence of 10–15%. Recent clinical data...

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Detalles Bibliográficos
Autores principales: Neumann, Olaf, Burn, Timothy C., Allgäuer, Michael, Ball, Markus, Kirchner, Martina, Albrecht, Thomas, Volckmar, Anna-Lena, Beck, Susanne, Endris, Volker, Goldschmid, Hannah, Lehmann, Ulrich, Seker-Cin, Huriye, Uhrig, Sebastian, Roessler, Stephanie, Budczies, Jan, Fröhling, Stefan, Longerich, Thomas, Wagner, Alex H., Vogel, Arndt, Schirmacher, Peter, Stenzinger, Albrecht, Kazdal, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553883/
https://www.ncbi.nlm.nih.gov/pubmed/35871236
http://dx.doi.org/10.1038/s41416-022-01908-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553883/
https://www.ncbi.nlm.nih.gov/pubmed/35871236
http://dx.doi.org/10.1038/s41416-022-01908-1

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