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Monobody adapter for functional antibody display on nanoparticles for adaptable targeted delivery applications

Vascular endothelial cells (ECs) play a central role in the pathophysiology of many diseases. The use of targeted nanoparticles (NPs) to deliver therapeutics to ECs could dramatically improve efficacy by providing elevated and sustained intracellular drug levels. However, achieving sufficient levels...

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Detalles Bibliográficos
Autores principales: Albert, C., Bracaglia, L., Koide, A., DiRito, J., Lysyy, T., Harkins, L., Edwards, C., Richfield, O., Grundler, J., Zhou, K., Denbaum, E., Ketavarapu, G., Hattori, T., Perincheri, S., Langford, J., Feizi, A., Haakinson, D., Hosgood, S. A., Nicholson, M. L., Pober, J. S., Saltzman, W. M., Koide, S., Tietjen, G. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553936/
https://www.ncbi.nlm.nih.gov/pubmed/36220817
http://dx.doi.org/10.1038/s41467-022-33490-8