A novel assessment of fine-motor function reveals early hindlimb and detectable forelimb deficits in an experimental model of ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder associated with the loss of cortical and spinal motor neurons (MNs) and muscle degeneration (Kiernan et al. in Lancet 377:942–955, 2011). In the preclinical setting, functional tests that can detect early changes in motor function i...

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Detalles Bibliográficos
Autores principales: Khademullah, C. Sahara, De Koninck, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553953/
https://www.ncbi.nlm.nih.gov/pubmed/36220871
http://dx.doi.org/10.1038/s41598-022-20333-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553953/
https://www.ncbi.nlm.nih.gov/pubmed/36220871
http://dx.doi.org/10.1038/s41598-022-20333-1

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