Safety and efficacy of oral fexinidazole in children with gambiense human African trypanosomiasis: a multicentre, single-arm, open-label, phase 2–3 trial

BACKGROUND: Fexinidazole has been reported as an effective oral monotherapy against non-severe gambiense human African trypanosomiasis in a recent trial in adults. We aimed to assess the safety and efficacy of fexinidazole in children across all disease stages of gambiense human African trypanosomia...

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Detalles Bibliográficos
Autores principales: Kande Betu Kumesu, Victor, Mutombo Kalonji, Wilfried, Bardonneau, Clélia, Valverde Mordt, Olaf, Ngolo Tete, Digas, Blesson, Séverine, Simon, François, Delhomme, Sophie, Bernhard, Sonja, Nganzobo Ngima, Pathou, Mahenzi Mbembo, Hélène, Fina Lubaki, Jean-Pierre, Lumeya Vuvu, Steven, Kuziena Mindele, Willy, Ilunga Wa Kyhi, Médard, Mandula Mokenge, Guylain, Kaninda Badibabi, Lewis, Kasongo Bonama, Augustin, Kavunga Lukula, Papy, Lumbala, Crispin, Scherrer, Bruno, Strub-Wourgaft, Nathalie, Tarral, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554014/
https://www.ncbi.nlm.nih.gov/pubmed/36179736
http://dx.doi.org/10.1016/S2214-109X(22)00338-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554014/
https://www.ncbi.nlm.nih.gov/pubmed/36179736
http://dx.doi.org/10.1016/S2214-109X(22)00338-2

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