Chemotherapy-induced infiltration of neutrophils promotes pancreatic cancer metastasis via Gas6/AXL signalling axis

OBJECTIVE: Pancreatic ductal adenocarcinoma (PDAC) is a highly metastatic disease and cytotoxic chemotherapy is the standard of care treatment for patients with advanced disease. Here, we investigate how the microenvironment in PDAC liver metastases reacts to chemotherapy and its role in metastatic...

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Detalles Bibliográficos
Autores principales: Bellomo, Gaia, Rainer, Carolyn, Quaranta, Valeria, Astuti, Yuliana, Raymant, Meirion, Boyd, Elzbieta, Stafferton, Ruth, Campbell, Fiona, Ghaneh, Paula, Halloran, Christopher M, Hammond, Dean E, Morton, Jennifer P, Palmer, Daniel, Vimalachandran, Dale, Jones, Robert, Mielgo, Ainhoa, Schmid, Michael C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Pancreas
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554050/
https://www.ncbi.nlm.nih.gov/pubmed/35022267
http://dx.doi.org/10.1136/gutjnl-2021-325272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554050/
https://www.ncbi.nlm.nih.gov/pubmed/35022267
http://dx.doi.org/10.1136/gutjnl-2021-325272

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