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The MASTL-ENSA-PP2A/B55 axis modulates cisplatin resistance in oral squamous cell carcinoma

Platinum-based chemotherapy is the standard first-line treatment for oral squamous cell carcinoma (OSCC) that is inoperable, recurrent, or metastatic. Platinum sensitivity is a major determinant of patient survival in advanced OSCC. Here, we investigated the involvement of MASTL, a cell cycle kinase...

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Detalles Bibliográficos
Autores principales: Gouttia, Odjo G., Zhao, Jing, Li, Yanqiu, Zwiener, Mackenzie J., Wang, Ling, Oakley, Gregory G., Peng, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554306/
https://www.ncbi.nlm.nih.gov/pubmed/36247015
http://dx.doi.org/10.3389/fcell.2022.904719