Cargando…

The MASTL-ENSA-PP2A/B55 axis modulates cisplatin resistance in oral squamous cell carcinoma

Platinum-based chemotherapy is the standard first-line treatment for oral squamous cell carcinoma (OSCC) that is inoperable, recurrent, or metastatic. Platinum sensitivity is a major determinant of patient survival in advanced OSCC. Here, we investigated the involvement of MASTL, a cell cycle kinase...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gouttia, Odjo G., Zhao, Jing, Li, Yanqiu, Zwiener, Mackenzie J., Wang, Ling, Oakley, Gregory G., Peng, Aimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554306/ https://www.ncbi.nlm.nih.gov/pubmed/36247015 http://dx.doi.org/10.3389/fcell.2022.904719

Ejemplares similares

PARP1 Upregulation in Recurrent Oral Cancer and Treatment Resistance
por: Wang, Feifei, et al.
Publicado: (2022)

The ATM-E6AP-MASTL axis mediates DNA damage checkpoint recovery
por: Li, Yanqiu, et al.
Publicado: (2023)

The Oncogenic Functions of MASTL Kinase
por: Marzec, Kamila, et al.
Publicado: (2018)

PP2A/B55 and Fcp1 Regulate Greatwall and Ensa Dephosphorylation during Mitotic Exit
por: Hégarat, Nadia, et al.
Publicado: (2014)

The BEG (PP2A-B55/ENSA/Greatwall) Pathway Ensures Cytokinesis follows Chromosome Separation
por: Cundell, Michael J., et al.
Publicado: (2013)

The ATM-E6AP-MASTL axis mediates DNA damage checkpoint recovery
por: Li, Yanqiu, et al.
Publicado: (2023)

Correction: PP2A/B55 and Fcp1 Regulate Greatwall and Ensa Dephosphorylation during Mitotic Exit
Publicado: (2014)

Therapeutic relevance of the PP2A-B55 inhibitory kinase MASTL/Greatwall in breast cancer
por: Álvarez-Fernández, Mónica, et al.
Publicado: (2017)

Discovery and Characterization of a Novel MASTL Inhibitor MKI-2 Targeting MASTL-PP2A in Breast Cancer Cells and Oocytes
por: Kang, Minsung, et al.
Publicado: (2021)

Structural, enzymatic and spatiotemporal regulation of PP2A-B55 phosphatase in the control of mitosis
por: Lacroix, Benjamin, et al.
Publicado: (2022)

Mastl/PP2A regulate Cdk1 in ooycte maturation
por: Adhikari, Deepak, et al.
Publicado: (2015)

Kinase-Independent Functions of MASTL in Cancer: A New Perspective on MASTL Targeting
por: Conway, James Ronald William, et al.
Publicado: (2020)

Ensa controls S-phase length by modulating Treslin levels
por: Charrasse, Sophie, et al.
Publicado: (2017)

LINC00261 Suppresses Cisplatin Resistance of Esophageal Squamous Cell Carcinoma Through miR-545-3p/MT1M Axis
por: Wang, Lijun, et al.
Publicado: (2021)

Mastl kinase, a promising therapeutic target, promotes cancer recurrence
por: Wang, Ling, et al.
Publicado: (2014)

PP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells
por: Rogers, Samuel, et al.
Publicado: (2016)

Dihydroartemisinin Sensitizes Esophageal Squamous Cell Carcinoma to Cisplatin by Inhibiting Sonic Hedgehog Signaling
por: Cui, Wei, et al.
Publicado: (2020)

ENSA and ARPP19 differentially control cell cycle progression and development
por: Hached, Khaled, et al.
Publicado: (2019)

HOTTIP-miR-205-ZEB2 Axis Confers Cisplatin Resistance to Ovarian Cancer Cells
por: Dong, Yu-Jie, et al.
Publicado: (2021)

Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development
por: Panicker, Nikita, et al.
Publicado: (2020)

Cisplatin-Resistant Gastric Cancer Cells Promote the Chemoresistance of Cisplatin-Sensitive Cells via the Exosomal RPS3-Mediated PI3K-Akt-Cofilin-1 Signaling Axis
por: Sun, Meng-Yao, et al.
Publicado: (2021)

MASTL: A novel therapeutic target for Cancer Malignancy
por: Fatima, Iram, et al.
Publicado: (2020)

SILAC kinase screen identifies potential MASTL substrates
por: Marzec, Kamila A., et al.
Publicado: (2022)

MASTL overexpression promotes chromosome instability and metastasis in breast cancer
por: Rogers, Samuel, et al.
Publicado: (2018)

Circ-ZDHHC5 Accelerates Esophageal Squamous Cell Carcinoma Progression in vitro via miR-217/ZEB1 Axis
por: Wang, Qian, et al.
Publicado: (2020)

Copy number amplification of ENSA promotes the progression of triple-negative breast cancer via cholesterol biosynthesis
por: Chen, Yi-Yu, et al.
Publicado: (2022)

MASTL inhibition promotes mitotic catastrophe through PP2A activation to inhibit cancer growth and radioresistance in breast cancer cells
por: Yoon, Yi Na, et al.
Publicado: (2018)

MASTL promotes cell contractility and motility through kinase-independent signaling
por: Taskinen, Maria Emilia, et al.
Publicado: (2020)

Selective dephosphorylation by PP2A-B55 directs the meiosis I-meiosis II transition in oocytes
por: Swartz, S Zachary, et al.
Publicado: (2021)

PP2A(Cdc55/B55), a possible therapeutic target in cyclin D1-dependent cancers
por: Noguchi, Eishi
Publicado: (2013)

Opa1 Prevents Apoptosis and Cisplatin-Induced Ototoxicity in Murine Cochleae
por: Dong, Tingting, et al.
Publicado: (2021)

Protein interactomes of protein phosphatase 2A B55 regulatory subunits reveal B55-mediated regulation of replication protein A under replication stress
por: Wang, Feifei, et al.
Publicado: (2018)

The Cell Cycle Checkpoint System MAST(L)-ENSA/ARPP19-PP2A is Targeted by cAMP/PKA and cGMP/PKG in Anucleate Human Platelets
por: Kumm, Elena J., et al.
Publicado: (2020)

Fcp1 phosphatase controls Greatwall kinase to promote PP2A-B55 activation and mitotic progression
por: Della Monica, Rosa, et al.
Publicado: (2015)

The Role of an IL-10/Hyaluronan Axis in Dermal Wound Healing
por: Singampalli, Kavya L., et al.
Publicado: (2020)

The Relationship Between Actin Cytoskeleton and Membrane Transporters in Cisplatin Resistance of Cancer Cells
por: Shimizu, Takahiro, et al.
Publicado: (2020)

ERas Enhances Resistance to Cisplatin-Induced Apoptosis by Suppressing Autophagy in Gastric Cancer Cell
por: Tian, Huajian, et al.
Publicado: (2020)

Isoalantolactone Increases the Sensitivity of Prostate Cancer Cells to Cisplatin Treatment by Inducing Oxidative Stress
por: Huang, Hang, et al.
Publicado: (2021)

The deubiquitinase USP8 regulates ovarian cancer cell response to cisplatin by suppressing apoptosis
por: Corno, Cristina, et al.
Publicado: (2022)

Cdc6 is sequentially regulated by PP2A-Cdc55, Cdc14, and Sic1 for origin licensing in S. cerevisiae
por: Philip, Jasmin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_kbe9nus92ltpeo9q2v13bjso1a