Cryoelectron microscopy structures of a human neutralizing antibody bound to MERS-CoV spike glycoprotein

Neutralizing monoclonal antibodies (mAbs) against highly pathogenic coronaviruses represent promising candidates for clinical intervention. Here, we isolated a potent neutralizing monoclonal antibody, MERS-S41, from a yeast displayed scFv library using the S protein as a bait. To uncover the neutral...

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Detalles Bibliográficos
Autores principales: Zhang, Shuyuan, Jia, Wenxv, Zeng, Jianwei, Li, Mingxi, Wang, Ziyi, Zhou, Haixia, Zhang, Linqi, Wang, Xinquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554411/
https://www.ncbi.nlm.nih.gov/pubmed/36246239
http://dx.doi.org/10.3389/fmicb.2022.988298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554411/
https://www.ncbi.nlm.nih.gov/pubmed/36246239
http://dx.doi.org/10.3389/fmicb.2022.988298

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