Cargando…
Physiologically-based pharmacokinetic modelling and dosing evaluation of gentamicin in neonates using PhysPK
Each year, infections caused around the 25% of neonatal deaths. Early empirical treatments help to reduce this mortality, although optimized dosing regimens are still lacking. The aims were to develop and validate a gentamicin physiologically-based pharmacokinetic (PBPK) model and then potentially e...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554458/ https://www.ncbi.nlm.nih.gov/pubmed/36249803 http://dx.doi.org/10.3389/fphar.2022.977372 |