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Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants

The emergence and global spread of the SARS-CoV-2 Omicron variants, which carry an unprecedented number of mutations, raise serious concerns due to the reduced efficacy of current vaccines and resistance to therapeutic antibodies. Here, we report the generation and characterization of two potent hum...

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Detalles Bibliográficos
Autores principales: Chen, Zhaochun, Zhang, Peng, Matsuoka, Yumiko, Tsybovsky, Yaroslav, West, Kamille, Santos, Celia, Boyd, Lisa F., Nguyen, Hanh, Pomerenke, Anna, Stephens, Tyler, Olia, Adam S., Zhang, Baoshan, De Giorgi, Valeria, Holbrook, Michael R., Gross, Robin, Postnikova, Elena, Garza, Nicole L., Johnson, Reed F., Margulies, David H., Kwong, Peter D., Alter, Harvey J., Buchholz, Ursula J., Lusso, Paolo, Farci, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554601/
https://www.ncbi.nlm.nih.gov/pubmed/36302375
http://dx.doi.org/10.1016/j.celrep.2022.111528