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In silico analysis of a SLC6A4 G100V mutation in lung cancers

SLC6A4 is a serotonin re-uptake transporter which has been a target for anti-depressant therapies but recently some mutations have been described in cancer cells. Here, we characterize mutations in SLC6A4 that appear in cancer cells. We employed several validated computational and artificial intelli...

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Detalles Bibliográficos
Autores principales: Pappula, Amrit L, Gibson, Louis N, Bouley, Renee A, Petreaca, Ruben C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554669/
https://www.ncbi.nlm.nih.gov/pubmed/36247322
http://dx.doi.org/10.17912/micropub.biology.000645