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PTS is activated by ATF4 and promotes lung adenocarcinoma development via the Wnt pathway

BACKGROUND: The effects and mechanism of 6-pyruvoyl-tetrahydropterin synthase (PTS) on lung adenocarcinoma (LUAD) were studied in LUAD cells and mice with subcutaneously transplanted tumors. METHODS: PTS level in tissues and cells was tested by immunohistochemistry, western blot, and quantitative re...

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Detalles Bibliográficos
Autores principales: Ma, Wei, Wang, Chao, Li, Ruzhen, Han, Zhaohui, Jiang, Yuanzhu, Zhang, Xiangwei, Divisi, Duilio, Capobianco, Enrico, Zhang, Lin, Dong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554678/
https://www.ncbi.nlm.nih.gov/pubmed/36248333
http://dx.doi.org/10.21037/tlcr-22-593