Identification of human MHC-I HPV18 E6/E7-specific CD8 + T cell epitopes and generation of an HPV18 E6/E7-expressing adenosquamous carcinoma in HLA-A2 transgenic mice

BACKGROUND: Human Papillomavirus type 18 (HPV18) is a high-risk HPV that is commonly associated with cervical cancer. HPV18 oncogenes E6 and E7 are associated with the malignant transformation of cells, thus the identification of human leukocyte antigen (HLA)-restricted E6/E7 peptide-specific CD8 + ...

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Detalles Bibliográficos
Autores principales: Peng, Shiwen, Xing, Deyin, Ferrall, Louise, Tsai, Ya-Chea, Hung, Chien-Fu, Wu, T.-C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554842/
https://www.ncbi.nlm.nih.gov/pubmed/36224625
http://dx.doi.org/10.1186/s12929-022-00864-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554842/
https://www.ncbi.nlm.nih.gov/pubmed/36224625
http://dx.doi.org/10.1186/s12929-022-00864-5

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