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Improving cancer immunotherapy by rationally combining oncolytic virus with modulators targeting key signaling pathways

Oncolytic viruses (OVs) represent a new class of multi-modal immunotherapies for cancer, with OV-elicited antitumor immunity being key to their overall therapeutic efficacy. Currently, the clinical effectiveness of OV as monotherapy remains limited, and thus investigators have been exploring various...

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Detalles Bibliográficos
Autores principales: Zhu, Zhi, McGray, A. J. Robert, Jiang, Weijian, Lu, Binfeng, Kalinski, Pawel, Guo, Zong Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554963/
https://www.ncbi.nlm.nih.gov/pubmed/36221123
http://dx.doi.org/10.1186/s12943-022-01664-z