Ruscogenin Protects Against Deoxynivalenol-Induced Hepatic Injury by Inhibiting Oxidative Stress, Inflammation, and Apoptosis Through the Nrf2 Signaling Pathway: An In vitro Study

BACKGROUND: Deoxynivalenol (DON) is a trichothecene mycotoxin with demonstrated cytotoxicity in several cell lines and animals, primarily owing to inflammation and reactive oxygen species accumulation. Ruscogenin (RGN), a steroidal sapogenin of Radix Ophiopogon japonicus, has significant anti-thromb...

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Detalles Bibliográficos
Autores principales: Elsawy, Hany, Rajendran, Peramaiyan, Sedky, Azza Mahmoud, Alfwuaires, Manal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555037/
https://www.ncbi.nlm.nih.gov/pubmed/36247053
http://dx.doi.org/10.4103/sjmms.sjmms_725_21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555037/
https://www.ncbi.nlm.nih.gov/pubmed/36247053
http://dx.doi.org/10.4103/sjmms.sjmms_725_21

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