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Delayed puberty, gonadotropin abnormalities and subfertility in male Padi2/Padi4 double knockout mice

BACKGROUND: Peptidylarginine deiminase enzymes (PADs) convert arginine residues to citrulline in a process called citrullination or deimination. Recently, two PADs, PAD2 and PAD4, have been linked to hormone signaling in vitro and the goal of this study was to test for links between PAD2/PAD4 and ho...

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Detalles Bibliográficos
Autores principales: Sams, Kelly L., Mukai, Chinatsu, Marks, Brooke A., Mittal, Chitvan, Demeter, Elena Alina, Nelissen, Sophie, Grenier, Jennifer K., Tate, Ann E., Ahmed, Faraz, Coonrod, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555066/
https://www.ncbi.nlm.nih.gov/pubmed/36224627
http://dx.doi.org/10.1186/s12958-022-01018-w