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Ultra-sensitive molecular detection of gene fusions from RNA using ASPYRE

BACKGROUND: RNA is a critical analyte for unambiguous detection of actionable mutations used to guide treatment decisions in oncology. Currently available methods for gene fusion detection include molecular or antibody-based assays, which suffer from either being limited to single-gene targeting, la...

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Detalles Bibliográficos
Autores principales: Gray, Eleanor R, Mordaka, Justyna M, Christoforou, Efthimia R, von Bargen, Kristine, Potts, Nicola D, Xyrafaki, Christina, Silva, Ana-Luisa, Stolarek-Januszkiewicz, Magdalena, Anton, Katarzyna, Powalowska, Paulina K, Andreazza, Simonetta, Tomassini, Alessandro, Palmer, Rebecca N, Cooke, Aishling, Osborne, Robert J, Balmforth, Barnaby W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555097/
https://www.ncbi.nlm.nih.gov/pubmed/36224552
http://dx.doi.org/10.1186/s12920-022-01363-0