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Ayurvedic formulations Guduchi and Madhuyashti triggers JNK signaling mediated immune response and adversely affects Huntington phenotype

BACKGROUND: Huntington’s disease manifests due to abnormal CAG trinucleotide expansion, in the first exon of the Huntingtin gene and disease progression involves genetic, immune, and environmental components. The pathogenesis is characterized by the formation of Inclusion Bodies, disruption of neuro...

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Detalles Bibliográficos
Autores principales: Singh, Surabhi, Tapadia, Madhu G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555103/
https://www.ncbi.nlm.nih.gov/pubmed/36224586
http://dx.doi.org/10.1186/s12906-022-03724-9