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Establishment of a bipedal rat model of lumbar facet joint osteoarthritis using intraarticular injection of urinary plasminogen activator

BACKGROUND: Previous studies have demonstrated that by injecting uPA into the lumbar facet joints (LFJ) of normal rats, a rat LFJOA animal model can be successfully established. However, there is no evidence that intraarticular injection of uPA can induce or much serious osteoarthritis in bipedal ra...

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Detalles Bibliográficos
Autores principales: Yang, Di, Hu, Wei, Li, Hao, Shao, Yin-chu, Shan, Ji-chun, Xiong, Xu, Shuang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555121/
https://www.ncbi.nlm.nih.gov/pubmed/36224572
http://dx.doi.org/10.1186/s13018-022-03339-3