Extracts from Argentinian native plants reverse fluconazole resistance in Candida species by inhibiting the efflux transporters Mdr1 and Cdr1

BACKGROUND: The development of multidrug resistance (MDR) associated with the overexpression of the efflux transporters Mdr1 and Cdr1 in Candida species impedes antifungal therapies. The urgent need for novel agents able to inhibit the function of both pumps, led us to evaluate this property in 137...

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Detalles Bibliográficos
Autores principales: Gil, Florimar, Laiolo, Jerónimo, Bayona-Pacheco, Brayan, Cannon, Richard D., Ferreira-Pereira, Antonio, Carpinella, María Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555179/
https://www.ncbi.nlm.nih.gov/pubmed/36224581
http://dx.doi.org/10.1186/s12906-022-03745-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555179/
https://www.ncbi.nlm.nih.gov/pubmed/36224581
http://dx.doi.org/10.1186/s12906-022-03745-4

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