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Heparin Protects Human Neural Progenitor Cells from Zika Virus-Induced Cell Death While Preserving Their Differentiation into Mature Neuroglial Cells

Zika virus (ZIKV) is an arbovirus member of the Flaviviridae family that causes severe congenital brain anomalies in infected fetuses. The key target cells of ZIKV infection, human neural progenitor cells (hNPCs), are highly permissive to infection that causes the inhibition of cell proliferation an...

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Detalles Bibliográficos
Autores principales: Pagani, Isabel, Ottoboni, Linda, Podini, Paola, Ghezzi, Silvia, Brambilla, Elena, Bezukladova, Svetlana, Corti, Davide, Bianchi, Marco Emilio, Capobianchi, Maria Rosaria, Poli, Guido, Panina-Bordignon, Paola, Yates, Edwin A., Martino, Gianvito, Vicenzi, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555206/
https://www.ncbi.nlm.nih.gov/pubmed/36121298
http://dx.doi.org/10.1128/jvi.01122-22