The Spike-Stabilizing D614G Mutation Interacts with S1/S2 Cleavage Site Mutations To Promote the Infectious Potential of SARS-CoV-2 Variants

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remained genetically stable during the first 3 months of the pandemic, before acquiring a D614G spike mutation that rapidly spread worldwide and then generating successive waves of viral variants with increasingly high transmissibility. We...

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Detalles Bibliográficos
Autores principales: Gellenoncourt, Stacy, Saunders, Nell, Robinot, Rémy, Auguste, Lucas, Rajah, Maaran Michael, Kervevan, Jérôme, Jeger-Madiot, Raphaël, Staropoli, Isabelle, Planchais, Cyril, Mouquet, Hugo, Buchrieser, Julian, Schwartz, Olivier, Chakrabarti, Lisa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555207/
https://www.ncbi.nlm.nih.gov/pubmed/36121299
http://dx.doi.org/10.1128/jvi.01301-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555207/
https://www.ncbi.nlm.nih.gov/pubmed/36121299
http://dx.doi.org/10.1128/jvi.01301-22

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