Cargando…

A model-informed approach to assess the risk of immune checkpoint inhibitor-induced autoimmune myocarditis

Immune checkpoint inhibitors (ICIs), as a novel immunotherapy, are designed to modulate the immune system to attack malignancies. Despite their promising benefits, immune-related adverse events (IRAEs) may occur, and incidences are bound to increase with surging demand of this class of drugs in trea...

Descripción completa

Detalles Bibliográficos
Autores principales: van der Vegt, Solveig A., Wang, Ying-Jie, Polonchuk, Liudmila, Wang, Ken, Waters, Sarah L., Baker, Ruth E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555336/
https://www.ncbi.nlm.nih.gov/pubmed/36249751
http://dx.doi.org/10.3389/fphar.2022.966180