Parafibromin governs cell polarity and centrosome assembly in Drosophila neural stem cells

Neural stem cells (NSCs) divide asymmetrically to balance their self-renewal and differentiation, an imbalance in which can lead to NSC overgrowth and tumor formation. The functions of Parafibromin, a conserved tumor suppressor, in the nervous system are not established. Here, we demonstrate that Dr...

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Detalles Bibliográficos
Autores principales: Deng, Qiannan, Wang, Cheng, Koe, Chwee Tat, Heinen, Jan Peter, Tan, Ye Sing, Li, Song, Gonzalez, Cayetano, Sung, Wing-Kin, Wang, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555638/
https://www.ncbi.nlm.nih.gov/pubmed/36223339
http://dx.doi.org/10.1371/journal.pbio.3001834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555638/
https://www.ncbi.nlm.nih.gov/pubmed/36223339
http://dx.doi.org/10.1371/journal.pbio.3001834

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