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Parafibromin governs cell polarity and centrosome assembly in Drosophila neural stem cells
Neural stem cells (NSCs) divide asymmetrically to balance their self-renewal and differentiation, an imbalance in which can lead to NSC overgrowth and tumor formation. The functions of Parafibromin, a conserved tumor suppressor, in the nervous system are not established. Here, we demonstrate that Dr...
Autores principales: | Deng, Qiannan, Wang, Cheng, Koe, Chwee Tat, Heinen, Jan Peter, Tan, Ye Sing, Li, Song, Gonzalez, Cayetano, Sung, Wing-Kin, Wang, Hongyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555638/ https://www.ncbi.nlm.nih.gov/pubmed/36223339 http://dx.doi.org/10.1371/journal.pbio.3001834 |
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