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HDAC6 inhibitor ACY-1083 shows lung epithelial protective features in COPD

Airway epithelial damage is a common feature in respiratory diseases such as COPD and has been suggested to drive inflammation and progression of disease. These features manifest as remodeling and destruction of lung epithelial characteristics including loss of small airways which contributes to chr...

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Detalles Bibliográficos
Autores principales: Horndahl, Jenny, Svärd, Rebecka, Berntsson, Pia, Wingren, Cecilia, Li, Jingjing, Abdillahi, Suado M., Ghosh, Baishakhi, Capodanno, Erin, Chan, Justin, Ripa, Lena, Åstrand, Annika, Sidhaye, Venkataramana K., Collins, Mia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555642/
https://www.ncbi.nlm.nih.gov/pubmed/36223404
http://dx.doi.org/10.1371/journal.pone.0266310