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HDAC6 inhibitor ACY-1083 shows lung epithelial protective features in COPD
Airway epithelial damage is a common feature in respiratory diseases such as COPD and has been suggested to drive inflammation and progression of disease. These features manifest as remodeling and destruction of lung epithelial characteristics including loss of small airways which contributes to chr...
Autores principales: | Horndahl, Jenny, Svärd, Rebecka, Berntsson, Pia, Wingren, Cecilia, Li, Jingjing, Abdillahi, Suado M., Ghosh, Baishakhi, Capodanno, Erin, Chan, Justin, Ripa, Lena, Åstrand, Annika, Sidhaye, Venkataramana K., Collins, Mia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555642/ https://www.ncbi.nlm.nih.gov/pubmed/36223404 http://dx.doi.org/10.1371/journal.pone.0266310 |
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