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Inhibition of RIP1-RIP3-mediated necroptosis attenuates renal fibrosis via Wnt3α/β-catenin/GSK-3β signaling in unilateral ureteral obstruction

Renal fibrosis represents the final common outcome of chronic kidney disease of virtually any etiology. However, the mechanism underlying the evolution of renal fibrosis remains to be addressed. This study sought to clarify whether RIP1-RIP3-mediated necroptosis is involved in renal fibrosis via Wnt...

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Detalles Bibliográficos
Autores principales: Piao, Shang Guo, Ding, Jun, Lin, Xue Jing, Nan, Qi Yan, Xuan, Mei Ying, Jiang, Yu Ji, Zheng, Hai Lan, Jin, Ji Zhe, Li, Can
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555645/
https://www.ncbi.nlm.nih.gov/pubmed/36223414
http://dx.doi.org/10.1371/journal.pone.0274116