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Pro-inflammatory megakaryocyte gene expression in murine models of breast cancer

Despite abundant research demonstrating that platelets can promote tumor cell metastasis, whether primary tumors affect platelet-producing megakaryocytes remains understudied. In this study, we used a spontaneous murine model of breast cancer to show that tumor burden reduced megakaryocyte number an...

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Detalles Bibliográficos
Autores principales: Roweth, Harvey G., Malloy, Michael W., Goreczny, Gregory J., Becker, Isabelle C., Guo, Qiuchen, Mittendorf, Elizabeth A., Italiano, Joseph E., McAllister, Sandra S., Battinelli, Elisabeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555784/
https://www.ncbi.nlm.nih.gov/pubmed/36223471
http://dx.doi.org/10.1126/sciadv.abo5224