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Pro-inflammatory megakaryocyte gene expression in murine models of breast cancer
Despite abundant research demonstrating that platelets can promote tumor cell metastasis, whether primary tumors affect platelet-producing megakaryocytes remains understudied. In this study, we used a spontaneous murine model of breast cancer to show that tumor burden reduced megakaryocyte number an...
Autores principales: | Roweth, Harvey G., Malloy, Michael W., Goreczny, Gregory J., Becker, Isabelle C., Guo, Qiuchen, Mittendorf, Elizabeth A., Italiano, Joseph E., McAllister, Sandra S., Battinelli, Elisabeth M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555784/ https://www.ncbi.nlm.nih.gov/pubmed/36223471 http://dx.doi.org/10.1126/sciadv.abo5224 |
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