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The Effect of Regularly Dosed Acetaminophen vs No Acetaminophen on Renal Function in Plasmodium knowlesi Malaria (PACKNOW): A Randomized, Controlled Trial( )

BACKGROUND: Acetaminophen inhibits cell-free hemoglobin-induced lipid peroxidation and improves renal function in severe falciparum malaria but has not been evaluated in other infections with prominent hemolysis, including Plasmodium knowlesi malaria. METHODS: PACKNOW was an open-label, randomized,...

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Detalles Bibliográficos
Autores principales: Cooper, Daniel J, Grigg, Matthew J, Plewes, Katherine, Rajahram, Giri S, Piera, Kim A, William, Timothy, Menon, Jayaram, Koleth, Glenn, Edstein, Michael D, Birrell, Geoffrey W, Wattanakul, Thanaporn, Tarning, Joel, Patel, Aatish, Wen Yeo, Tsin, Dondorp, Arjen M, Anstey, Nicholas M, Barber, Bridget E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555834/
https://www.ncbi.nlm.nih.gov/pubmed/35180298
http://dx.doi.org/10.1093/cid/ciac152