Macrophage innate training induced by IL-4 and IL-13 activation enhances OXPHOS driven anti-mycobacterial responses

Macrophages are a highly adaptive population of innate immune cells. Polarization with IFNγ and LPS into the ‘classically activated’ M1 macrophage enhances pro-inflammatory and microbicidal responses, important for eradicating bacteria such as Mycobacterium tuberculosis. By contrast, ‘alternatively...

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Detalles Bibliográficos
Autores principales: Lundahl, Mimmi LE, Mitermite, Morgane, Ryan, Dylan Gerard, Case, Sarah, Williams, Niamh C, Yang, Ming, Lynch, Roisin I, Lagan, Eimear, Lebre, Filipa M, Gorman, Aoife L, Stojkovic, Bojan, Bracken, Adrian P, Frezza, Christian, Sheedy, Frederick J, Scanlan, Eoin M, O'Neill, Luke AJ, Gordon, Stephen V, Lavelle, Ed C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555863/
https://www.ncbi.nlm.nih.gov/pubmed/36173104
http://dx.doi.org/10.7554/eLife.74690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555863/
https://www.ncbi.nlm.nih.gov/pubmed/36173104
http://dx.doi.org/10.7554/eLife.74690

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