Rapid, Reference-Free human genotype imputation with denoising autoencoders

Genotype imputation is a foundational tool for population genetics. Standard statistical imputation approaches rely on the co-location of large whole-genome sequencing-based reference panels, powerful computing environments, and potentially sensitive genetic study data. This results in computational...

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Detalles Bibliográficos
Autores principales: Dias, Raquel, Evans, Doug, Chen, Shang-Fu, Chen, Kai-Yu, Loguercio, Salvatore, Chan, Leslie, Torkamani, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555874/
https://www.ncbi.nlm.nih.gov/pubmed/36148981
http://dx.doi.org/10.7554/eLife.75600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555874/
https://www.ncbi.nlm.nih.gov/pubmed/36148981
http://dx.doi.org/10.7554/eLife.75600

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