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Chemoprevention of 4NQO-Induced Mouse Tongue Carcinogenesis by AKT Inhibitor through the MMP-9/RhoC Signaling Pathway and Autophagy

Oral cancer (OC), the most common cancer in the head and neck, which has a poor prognosis, histopathologically follows a stepwise pattern of hyperplasia, dysplasia, and cancer. Blocking the progression of OC in the precancer stage could greatly improve the survival and cure rates. AKT protein plays...

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Detalles Bibliográficos
Autores principales: Yin, Panpan, Chen, Jiahui, Wu, Yanlin, Gao, Feng, Wen, Jinlin, Zhang, Wenbin, Su, Ying, Zhang, Xinyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556259/
https://www.ncbi.nlm.nih.gov/pubmed/36247874
http://dx.doi.org/10.1155/2022/3770715