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Biocompatible Cationic Lipoamino Acids as Counterions for Oral Administration of API-Ionic Liquids

PURPOSE: The use of ionic liquids (ILs) in drug delivery has focused attention on non-toxic IL counterions. Cationic lipids can be used to form ILs with weakly acidic drugs to enhance drug loading in lipid-based formulations (LBFs). However, cationic lipids are typically toxic. Here we explore the u...

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Detalles Bibliográficos
Autores principales: Lai, Anthony, Leong, Nathania, Zheng, Dan, Ford, Leigh, Nguyen, Tri-Hung, Williams, Hywel D., Benameur, Hassan, Scammells, Peter J., Porter, Christopher J. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556374/
https://www.ncbi.nlm.nih.gov/pubmed/35661084
http://dx.doi.org/10.1007/s11095-022-03305-y