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Predicting the structure of large protein complexes using AlphaFold and Monte Carlo tree search
AlphaFold can predict the structure of single- and multiple-chain proteins with very high accuracy. However, the accuracy decreases with the number of chains, and the available GPU memory limits the size of protein complexes which can be predicted. Here we show that one can predict the structure of...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556563/ https://www.ncbi.nlm.nih.gov/pubmed/36224222 http://dx.doi.org/10.1038/s41467-022-33729-4 |