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Immunogenicity of MultiTEP platform technology-based Tau vaccine in non-human primates

Pathological forms of Tau protein are directly associated with neurodegeneration and correlate with Alzheimer’s Disease (AD) symptoms, progression, and severity. Previously, using various mouse models of Tauopathies and AD, we have demonstrated the immunogenicity and efficacy of the MultiTEP-based a...

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Detalles Bibliográficos
Autores principales: Hovakimyan, Armine, Zagorski, Karen, Chailyan, Gor, Antonyan, Tatevik, Melikyan, Levon, Petrushina, Irina, Batt, Dash G., King, Olga, Ghazaryan, Manush, Donthi, Aashrit, Foose, Caitlynn, Petrovsky, Nikolai, Cribbs, David H., Agadjanyan, Michael G., Ghochikyan, Anahit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556597/
https://www.ncbi.nlm.nih.gov/pubmed/36224191
http://dx.doi.org/10.1038/s41541-022-00544-3